Side Effects Of Cisplatin Based Chemotherapy

In total a cancer patient can experience any combination of around 40 specific side effects.

Side effects of cisplatin based chemotherapy. The platinum based drugs cisplatin carboplatin and oxaliplatin are regularly prescribed in the treatment of cancer and while they are effective their use is limited by their severe dose limiting side effects also referred to as adverse effects events. One notable example is heart damage following treatment with adriamycin doxorubicin with this drug a possible long term side effect is weakening of the heart muscle resulting in a decreased ability to pump blood through the body heart failure. There is no relationship between the presence or severity of cisplatin side effects and effectiveness of cisplatin. Also your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Nephrotoxicity dose related and cumulative renal insufficiency is the major dose limiting toxicity of cis platin. These side effects may go away during treatment as your body adjusts to the medicine. Also your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Some side effects may occur that usually do not need medical attention.

There are many options to help minimize or prevent the side effects of cisplatin. The following side effects are common. Cisplatin is platinum based and was the first medicine developed in that drug class. These include testicular cancer ovarian cancer cervical cancer breast cancer bladder cancer head and neck cancer esophageal cancer lung cancer mesothelioma brain tumors and neuroblastoma.

Cisplatin side effects will improve after therapy is complete. Cisplatin side effects may be quite manageable. It is best to read this information with our general information about chemotherapy and the type of cancer you have. Cisplatin is a chemotherapy medication used to treat a number of cancers.

Chemotherapy can cause cardiac effects early in treatment but in some cases the effects may not show up until much later. The information is not intended to cover all possible uses directions precautions drug interactions or adverse effects nor should it be construed to indicate that use of a particular drug is. Side effects not requiring immediate medical attention. Common side effects include bone marrow suppression hearing problems kidney problems.

Other drugs in this class include carboplatin a drug with fewer and less severe side effects introduced in the 1980s and oxaliplatin a drug which is part of the folfox treatment for colorectal cancer. Cisplatin is a chemotherapy drug used to treat testicular ovarian bladder head and neck lung and cervical cancer it may also be used to treat other cancers. These side effects may go away during treatment as your body adjusts to the medicine. Renal toxicity has been noted in 28 to 36 of patients treated with a single dose of 50 mg m 2 it is first noted during the second week after a dose and is manifested by elevations in bun and creatinine serum uric acid and or a decrease in creatinine clearance.