Side Effects Of Car T Cell Therapy

Another potential side effect of car t cell therapy an off target effect is a mass die off of b cells known as b cell aplasia.

Side effects of car t cell therapy. Car t cell therapy side effects. Car t cell therapy is a type of immunotherapy that s offering hope to some non hodgkin lymphoma patients but the side effects are different from those of other cancer treatments. The studies examined cytokine release syndrome and neurologic toxicities. Learn how it s done it s side effects and if it s right for you.

The most common side effects seen are. Instead car t cell therapy can lead to a short lived but severe reaction called cytokine release syndrome. Cytokine release syndrome which is similar to flu like symptoms headache. Car t cell therapy is a form of immunotherapy in which patients t cells are modified to become better at tracking down and destroying tumor cells.

Felipe samaniego m d shares what to know. Cd19 is also expressed on normal b cells which are responsible for producing antibodies that kill pathogens. Car t cells are made by extracting thousands of a patient s t cells sending them to a lab where they re outfitted with genes and proteins that improve their cancer fighting prowess and then re infusing them into the patient. These include neurotoxicity which can result in headache confusion and.

These normal b cells are also often killed by the infused car t cells. Severe muscle or joint pain shortness of breath low blood pressure and fast heart rate. Car t cell therapy is often called the next big breakthrough in cancer treatment. Some people have had serious side effects from this treatment especially as the car t cells multiply in the body to fight the cancer.

Despite the therapeutic successes of car t cell therapy the intervention carries the risk of severe side effects. Risks and side effects. You won t have hair loss that commonly follows chemotherapy. The side effects you may have and how serious they are will depend on how healthy you are before treatment your type of cancer how advanced it is the type of t cell transfer therapy you are receiving and the dose.

T cell transfer therapy can cause side effects which people experience in different ways. Severe nausea vomiting diarrhea. As car t cells multiply they cause massive amounts of chemicals called cytokines to be released into the blood.